Geriatrics & Chronic Care
Falls, pills, and function — the levers that keep elders independent
Falls and frailty
Ask every year. Falls are the leading cause of injury and of accidental death in adults 65 and older. Screen annually by asking about falls and observing gait and balance. A Timed Up-and-Go (stand from a chair, walk 3 meters, return, and sit) taking 12 seconds or longer flags high fall risk. Causes are usually multifactorial: medications, poor vision, orthostatic hypotension, weakness or gait disorders, and environmental hazards.
Prevention that works. Combine interventions aimed at the patient's specific risks:
- Review and reduce culprit medications, especially sedatives and antihypertensives
- Strength, gait, and balance exercise (physical therapy, tai chi)
- Vitamin D if deficient
- Vision correction (glasses, cataract surgery)
- Treat orthostatic hypotension
- Home-safety changes: grab bars, lighting, removing loose rugs
Exercise has the strongest trial evidence for preventing falls in community-dwelling older adults (USPSTF). In an older adult who is falling, pair it with a medication review that deprescribes sedating drugs.
Frailty (Fried phenotype). Five criteria: unintentional weight loss, exhaustion, weak grip strength, slow walking speed, and low physical activity. Three or more criteria means frail; one or two means pre-frail. Frailty predicts falls, disability, hospitalization, and death, and it should shape how aggressive care plans are.
Medications: Beers criteria and deprescribing
Polypharmacy. Taking five or more medications raises the risk of drug interactions, falls, and adverse events, and each new symptom tempts a prescribing cascade (a new drug to treat the side effect of an old one). Review the list at every visit and deprescribe drugs without a clear current indication or benefit.
Beers criteria. The Beers criteria list medications that are potentially inappropriate in older adults because safer alternatives exist.
| Drug class | Examples | Main harm |
|---|---|---|
| Benzodiazepines and Z-drugs | Lorazepam, diazepam, zolpidem | Falls, fractures, delirium |
| First-generation antihistamines | Diphenhydramine, hydroxyzine | Anticholinergic: confusion, urinary retention |
| Other anticholinergics | Oxybutynin, tricyclic antidepressants | Confusion, constipation, falls |
| Sulfonylureas (avoid as first- or second-line) | Glyburide, glimepiride highest risk; glipizide if one must be used | Prolonged hypoglycemia |
| Skeletal muscle relaxants | Cyclobenzaprine, methocarbamol | Sedation, anticholinergic effects |
| Chronic NSAIDs | Ibuprofen, naproxen | GI bleeding, kidney injury, fluid retention |
| Antipsychotics in dementia | Any, for behavior alone | Stroke and increased mortality |
Cognition: the 3 Ds
Rule out delirium first. Delirium is a medical emergency with an underlying trigger (infection such as UTI, drugs, metabolic derangement, urinary retention, pain, sleep loss). Dementia is itself a major risk factor for delirium, so a sudden decline in a patient with dementia is delirium until proven otherwise. The hypoactive form, with a quiet and withdrawn patient, is the one most often missed.
| Feature | Delirium | Dementia | Depression ("pseudodementia") |
|---|---|---|---|
| Onset | Acute, over hours to days | Insidious, over months to years | Subacute, often with a mood change |
| Course | Fluctuating | Chronic, progressive | Tracks mood |
| Attention and consciousness | Inattention; clouded consciousness | Alert until late | Alert |
| Testing behavior | Cannot sustain attention | Tries, confabulates, or covers gaps | Poor effort; "I don't know" answers |
| Reversibility | Often reversible; find the trigger | Usually irreversible; check B12 and TSH for reversible mimics | Improves with treatment |
Confusion Assessment Method (CAM). Delirium requires an acute onset or fluctuating course plus inattention, and either disorganized thinking or an altered level of consciousness. Manage by treating the cause, then use nonpharmacologic measures: reorientation, glasses and hearing aids, sleep protection, early mobilization, and avoiding restraints. Reserve low-dose antipsychotics for dangerous agitation, and avoid benzodiazepines except in alcohol or sedative withdrawal.
Dementia screening. Use the Mini-Cog (clock draw plus 3-word recall), the MoCA (more sensitive for mild cognitive impairment), or the MMSE.
Function, continence, and skin
ADLs vs IADLs. Basic ADLs (DEATH) are Dressing, Eating, Ambulating, Toileting, and Hygiene. Instrumental ADLs (SHAFT) are Shopping, Housekeeping, Accounting (finances), Food preparation, and Transportation. IADLs decline first; loss of basic ADLs signals a need for more care.
Urinary incontinence. Check a urinalysis and post-void residual, and look for reversible contributors (UTI, diuretics, anticholinergics, hyperglycemia, constipation). Then match therapy to the mechanism.
| Type | Mechanism | Clue | Treatment |
|---|---|---|---|
| Urge | Detrusor overactivity | Sudden urgency, large leaks | Bladder training first, then antimuscarinics (oxybutynin, tolterodine) or a β3 agonist (mirabegron, vibegron), preferred when anticholinergic or cognitive risk is a concern |
| Stress | Urethral hypermobility | Leaks with cough, laugh, or exertion; no urgency | Pelvic floor (Kegel) exercises, pessary, midurethral sling |
| Overflow | Retention (BPH, neurogenic bladder) | Dribbling, high post-void residual | Relieve obstruction (tamsulosin for BPH) or catheterize |
| Functional | Normal tract; cannot reach the toilet (mobility or cognition) | Dementia or immobility | Scheduled voiding, improved access |
Pressure injuries (pressure ulcers). Prevent them by repositioning at least every 2 hours, offloading the heels and sacrum, using pressure-redistributing surfaces, managing moisture, and optimizing nutrition. Assess risk with the Braden scale.
- Stage 1Intact skin with nonblanchable erythema.
- Stage 2Partial-thickness loss: blister or shallow ulcer, no fat visible.
- Stage 3Full-thickness loss into subcutaneous fat; no bone, muscle, or tendon exposed.
- Stage 4Exposed bone, muscle, or tendon.
A wound base hidden by slough or eschar is unstageable until it is cleared. Intact purple or maroon skin is a deep tissue pressure injury.
Advance care planning and chronic care
Documents. A living will states which treatments the patient would or would not want. A durable power of attorney for healthcare (healthcare proxy) names a surrogate decision-maker and is broadly authoritative, covering situations no document anticipated. A POLST turns goals into portable medical orders that follow the patient across settings.
Surrogate standards. Surrogates use substituted judgment (what the patient would have wanted), not their own preferences. When the patient's wishes are unknown, they fall back on the patient's best interests. Without an appointed proxy, the next of kin serves in the order set by state law.
Supporting caregivers. Assess caregiver burden routinely and connect families to respite care and community support. This prevents burnout, which is a risk factor for elder neglect.