Urologic Emergencies & Stones (Clinical)
When acting beats imaging: torsion, retention, the infected stone, and more
The acute scrotum
Testicular torsion. Sudden, severe unilateral testicular pain (often waking the patient, with nausea and vomiting), a high-riding testis with a horizontal lie, an absent cremasteric reflex, and a negative Prehn sign (no relief with elevation). It peaks in adolescents with a bell-clapper deformity, in which the testis is not anchored to the tunica vaginalis and can twist on its cord.
Act before imaging. Torsion is a surgical emergency: explore and detorse within 6 hours to salvage the testis, then perform bilateral orchiopexy, because the contralateral side shares the deformity. Salvage rates fall sharply after 6 hours, so a clinical diagnosis goes straight to the operating room. If Doppler ultrasound is obtained in an equivocal case, it shows decreased or absent testicular blood flow. A nonviable testis is removed.
Manual detorsion (rotating the testis outward, like opening a book) can buy time when the operating room is delayed, but it never replaces surgical exploration and orchiopexy.
| Feature | Testicular torsion | Epididymitis | Torsion of appendix testis |
|---|---|---|---|
| Onset | Sudden, severe | Gradual; often dysuria | Subacute, localized |
| Exam | High-riding testis, horizontal lie | Tender epididymis, normal lie | Tender upper-pole nodule, "blue dot" sign |
| Cremasteric reflex | Absent | Intact | Intact |
| Prehn sign | Negative (no relief) | Positive (relief with elevation) | Not helpful |
| Doppler | Decreased or absent flow | Increased flow | Normal testicular flow |
| Management | Detorsion within 6 h, bilateral orchiopexy | Antibiotics | Analgesics; self-limited |
Epididymitis therapy by likely organism (CDC 2021). Men under 35 usually have Chlamydia or gonorrhea: treat with ceftriaxone 500 mg IM once plus doxycycline 100 mg twice daily for 10 days. Men over 35 usually have Escherichia coli or other enteric organisms (often with BPH or instrumentation): treat with levofloxacin 500 mg daily for 10 days, only when gonorrhea is excluded, because a fluoroquinolone alone does not cover it. Men who practice insertive anal sex need coverage of both: ceftriaxone plus levofloxacin.
Acute urinary retention
Presentation. Sudden inability to void, suprapubic pain, and a palpably distended bladder. Precipitants include BPH, anticholinergics and opioids (and sympathomimetics such as decongestants), the postoperative state, and neurologic causes such as cord compression.
Management. Immediate bladder catheterization is both diagnostic and therapeutic; a bladder scan documents the retained volume. If a urethral catheter cannot pass, place a suprapubic catheter. After decompression, watch for postobstructive diuresis. In BPH, starting an α-blocker before a trial without the catheter improves the chance of voiding.
Kidney stones
Renal colic. A ureteral stone causes severe colicky flank pain radiating to the groin, hematuria, and a patient writhing in pain (unlike peritonitis, where patients lie still). Noncontrast CT of the abdomen and pelvis is the gold-standard test; ultrasound is used first in pregnancy and children to avoid radiation. NSAIDs are first-line analgesia.
- Under 5 mm: usually passes spontaneously with hydration and tamsulosin (medical expulsive therapy).
- 5–10 mm: may need intervention if it does not pass.
- Over 10 mm or refractory: shockwave lithotripsy or ureteroscopy.
- Staghorn calculi: percutaneous nephrolithotomy.
The infected obstructing stone. An obstructing stone with superimposed urinary infection (fever, pyuria) means pyonephrosis and impending urosepsis. Other reasons for urgent intervention are AKI, obstruction of a solitary kidney, and intractable pain or vomiting.
- RecognizeObstructing stone plus fever or pyuria.
- ResuscitateIV fluids and IV antibiotics covering gram-negatives.
- Decompress emergentlyPercutaneous nephrostomy tube or ureteral stent.
- Remove the stone laterDefinitive treatment only after the infection clears.
Never treat the stone itself (lithotripsy, ureteroscopy) in an infected, obstructed system before it is drained.
| Stone | Setting | Imaging and crystals | Prevention or treatment |
|---|---|---|---|
| Calcium oxalate | Most common; hypercalciuria, hypocitraturia, fat malabsorption (enteric hyperoxaluria) | Radiopaque; envelope-shaped crystals | Fluids, thiazide for hypercalciuria, citrate; keep normal dietary calcium |
| Struvite | Urease-producing organisms (Proteus, Klebsiella) in alkaline urine; staghorn calculi | Radiopaque; coffin-lid crystals | Remove the whole stone and treat the infection |
| Uric acid | Acidic urine; gout, high cell turnover | Radiolucent: missed on plain film, seen on CT | Alkalinize the urine to dissolve; allopurinol if hyperuricosuric |
| Cystine | Children with cystinuria | Hexagonal crystals | Hydration, urinary alkalinization |
General prevention. High fluid intake is the cornerstone for every stone type, with less sodium and animal protein. Restricting dietary calcium backfires, because gut calcium binds oxalate and limits its absorption.
Fournier gangrene and penile emergencies
Fournier gangrene. This is polymicrobial necrotizing fasciitis of the perineum and genitalia, typically in diabetic or immunocompromised men. Findings are severe pain out of proportion to the exam, crepitus, skin necrosis, and systemic toxicity.
Treat Fournier gangrene with emergent wide surgical debridement plus broad-spectrum IV antibiotics; do not delay surgery for imaging, because delay is fatal. Repeat debridement is often needed.
Priapism is an erection lasting more than 4 hours, and the key question is ischemic or not.
| Feature | Ischemic (low-flow) | Non-ischemic (high-flow) |
|---|---|---|
| Mechanism | Trapped venous blood; a compartment syndrome of the corpora | Unregulated inflow from a cavernosal artery fistula |
| Causes | Sickle cell disease, trazodone, PDE5 inhibitors, intracavernosal injections | Perineal or penile trauma |
| Exam | Painful, rigid | Non-painful, less rigid |
| Corporal blood gas | Dark, hypoxic, acidotic | Bright red, arterial |
| Treatment | Emergent corporal aspiration and intracavernosal phenylephrine | Less urgent: often observation or embolization |
Paraphimosis. A retracted foreskin trapped behind the glans causes painful glans edema and venous congestion, a true emergency. Reduce it manually by compressing the glans to squeeze out the edema and pulling the foreskin forward; perform a dorsal slit if reduction fails. It is often iatrogenic, when the foreskin is not replaced after catheterization or examination.
Paraphimosis (foreskin stuck behind the glans) is the emergency; phimosis (foreskin that cannot be retracted) usually is not, and it is physiologic in young boys.