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Step 2 CK · Psychiatry

Psychotherapy Modalities & Matching to Disorders

Every disorder has a signature therapy — know the match

Psychiatry·Psychopharmacology & Psychotherapy·6 min read·9 high-yield points·Reviewed by Veli Bakalov, MD @HemeOncBuddy
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Core principles: cognition and learning

Cognitive behavioral therapy. CBT holds that distorted automatic thoughts drive painful emotions and unhelpful behavior. In a structured, time-limited course (about 12–20 sessions), patient and therapist identify automatic negative thoughts, test them against evidence, and rehearse change through behavioral experiments and homework. It is first-line psychotherapy for depression, GAD, panic disorder, social anxiety disorder, bulimia nervosa, and binge-eating disorder. Typical distortions are all-or-nothing thinking, catastrophizing, overgeneralization, personalization, mind reading, emotional reasoning, and "should" statements.

Classical conditioning (Pavlov). A neutral stimulus paired with an unconditioned stimulus comes to evoke an involuntary response on its own. Phobias can be learned this way, and exposure unlearns them by extinction: the cue recurs without the feared outcome. Aversion therapy reverses the logic, pairing an unwanted behavior with an unpleasant stimulus (bitter polish for nail biting); disulfiram acts as a pharmacologic deterrent on a similar idea.

Operant conditioning (Skinner). Consequences shape voluntary behavior. Positive reinforcement adds a reward and negative reinforcement removes an aversive stimulus, and both increase the behavior; punishment decreases it; extinction follows when reinforcement stops. Contingency management, token economies, and parent management training apply these rules.

Negative reinforcement is not punishment: the seatbelt alarm stops once you buckle, so buckling increases.

Reinforcement schedules
ScheduleReward givenPatternExtinction
ContinuousEvery responseFastest acquisitionFastest
Fixed ratioAfter a set number of responsesHigh rate, pause after rewardFaster than variable
Fixed intervalFirst response after a set timeScalloped, peaks near deadlineFaster than variable
Variable intervalAfter unpredictable time (pop quiz)Slow, steadySlow
Variable ratioAfter unpredictable number (slot machine)High, steadySlowest

Depression, anxiety, and insomnia

  1. Mild MDDCBT, IPT, behavioral activation, or an SSRI; efficacy is similar, so patient preference decides.
  2. Moderate–severe or chronic MDDPsychotherapy plus an antidepressant, which outperforms either alone.
  3. Psychotic or life-threatening MDDECT (safe and highly effective), or an antidepressant plus an antipsychotic for psychotic features; refusal to eat or drink favors ECT.

Interpersonal therapy. IPT (about 12–16 weekly sessions) ties symptoms to one current problem area: grief, role disputes, role transitions (retirement, divorce, a new baby), or interpersonal deficits. It is evidence-based for MDD, favored in perinatal depression when the patient wants to avoid drug exposure, and a slower-acting alternative to CBT for bulimia. Postpartum blues, by contrast, resolve within 2 weeks and need only reassurance.

Panic disorder and GAD. CBT for panic adds interoceptive exposure (deliberately provoking palpitations or dizziness by hyperventilating or spinning until the sensations lose their threat) to restructuring of catastrophic misinterpretations. CBT for GAD targets worry with restructuring, worry exposure, and applied relaxation.

CBT for insomnia. CBT-I is first-line for chronic insomnia (≥3 nights per week for ≥3 months) at any age, and its gains persist after treatment, unlike those of hypnotics, which are second-line; sedating antihistamines are not recommended. Components are stimulus control (bed only for sleep and sex, get up if awake about 20 minutes, fixed wake time, no naps), sleep restriction (time in bed limited to actual sleep time, then extended), cognitive restructuring, and relaxation.

Sleep hygiene advice alone is not adequate treatment; it is one component of CBT-I.

OCD, trauma, and phobias

OCD. Exposure and response prevention has the patient confront the trigger (a "contaminated" doorknob) while withholding the ritual (handwashing), so anxiety peaks and then habituates. It is first-line alone or with an SSRI, often at high doses. Reassurance-seeking acts as a compulsion, so families are coached to stop supplying it.

PTSD. Trauma-focused psychotherapy is first-line: prolonged exposure (imaginal retelling plus in-vivo approach to avoided cues), cognitive processing therapy (challenging "stuck points" such as self-blame), EMDR (trauma recall during bilateral eye movements), and trauma-focused CBT for children. If therapy is unavailable or declined, use sertraline, paroxetine, fluoxetine, or venlafaxine.

Avoid benzodiazepines in PTSD: they worsen outcomes and hinder exposure learning. Single-session psychological debriefing does not prevent PTSD.

Specific phobia. Exposure is first-line. Systematic desensitization teaches relaxation and then climbs a fear hierarchy from least to most feared, imagined or in vivo; it rests on Wolpe's reciprocal inhibition, since relaxation is incompatible with anxiety. Flooding starts with prolonged, maximal exposure and no escape until fear extinguishes: faster, but more distressing. Medication has little role beyond an as-needed benzodiazepine for a rare unavoidable exposure such as a flight.

Personality, eating, childhood, and habit disorders

Dialectical behavior therapy. Linehan's DBT blends CBT with mindfulness to balance acceptance and change, combining weekly individual therapy, group skills training, and phone coaching in mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness. It reduces self-harm, suicide attempts, and hospitalizations in borderline personality disorder; medication is only adjunctive.

Eating disorders. Family-based (Maudsley) treatment is first-line for medically stable adolescents with anorexia: parents take charge of refeeding, then gradually hand control of eating back to the teen. Adults with anorexia receive individual therapy such as enhanced CBT. Bulimia is treated with CBT first, IPT as an alternative, and fluoxetine as the approved drug.

Parent management training. For ODD and conduct disorder, parents learn operant tools: consistent praise and rewards, clear commands, time-outs, and predictable consequences. Stimulants treat comorbid ADHD, and antipsychotics are reserved for severe aggression.

Habit reversal training. HRT pairs awareness training (recognizing urges and warning signs) with a physically incompatible competing response (clenching fists, sitting on the hands) and social support. It is first-line for trichotillomania and excoriation disorder and is the core of CBIT for Tourette and chronic tic disorders. Hair pulling must be told apart from alopecia areata and tinea capitis, which need medical treatment.

Substance use disorders

Motivational interviewing. MI is an empathic, nonjudgmental style that elicits the patient's own reasons for change ("change talk"), explores ambivalence, and builds self-efficacy through open questions, affirmations, reflections, and summaries rather than lecturing or confrontation. It fits precontemplation and contemplation best; disulfiram presumes a patient already committed to abstinence.

  1. PrecontemplationNo intention to change; raise awareness.
  2. ContemplationAmbivalent; weigh pros and cons.
  3. PreparationPlans to act within a month; set a quit date.
  4. ActionChanging for under 6 months; build coping skills and support.
  5. MaintenanceSustained 6 months or more; prevent relapse, which can recycle any stage.

Contingency management. Vouchers or prize draws reward objectively verified abstinence (negative urine toxicology), escalating with consecutive negative tests and resetting after a positive one. It has the strongest evidence for stimulant (cocaine, methamphetamine) use disorder, which has no FDA-approved medication.

Psychodynamic and supportive therapy

Psychodynamic therapy explores unconscious conflicts, defense mechanisms, early relationships, and transference to build insight; it suits motivated, psychologically minded patients with personality or long-standing relational problems. Psychoanalysis is its most intensive form.

Transference is the patient redirecting feelings about past figures onto the therapist; countertransference is the therapist's emotional reaction to the patient.

Supportive therapy strengthens existing defenses through empathy, reassurance, advice, and problem-solving; it suits acute crisis, severe mental or medical illness, and limited capacity for insight.

Matching psychotherapy to disorder
DisorderFirst-line psychotherapyKey point
DepressionCBT, IPT, behavioral activationAdd drug if moderate–severe
Panic, GAD, social anxietyCBTInteroceptive exposure for panic
Chronic insomniaCBT-IBefore hypnotics
OCDExposure and response prevention± high-dose SSRI
PTSDProlonged exposure, CPT, EMDRNo benzodiazepines
Specific phobiaSystematic desensitization, graded exposureFlooding is harsher
Borderline, chronic self-harmDBTDrugs only adjunctive
Adolescent anorexiaFamily-based treatmentParents direct refeeding
ODD, conduct disorderParent management trainingOperant rewards
Hair pulling, skin picking, ticsHabit reversal (CBIT)Competing response
Substance useMI; contingency managementCM best for stimulants